89 North | Flash Photolysis System

High Power Flash Lamp from Cairn Research Limited Combined with the ULTRASTABLE PhotoFluor II Fluorescence Illumination System

Applications

Uncaging Studies

  • Neurotransmitter studies via caged carbamylcholine carbachol, y-aminobutyric acid and L-glutamic acid
  • Manipulation of intracellular calcium levels via caged Ca2+ chelators
  • RNA interference studies via caged siRNAs
  • Study of signal transduction pathways with caged nucleotides
  • Study of second messenger signaling cascades with caged inositol 1,4,5-triphosphate and/or caged cADP-ribose

Photoactivation/Photoconversion of Fluorescent Proteins

  • PA-GFP
  • Dronpa
  • tdEOS

Features

  • Variable charge capacitance of the flash lamp allows for fine control of the flash/photoactivation light intensity
  • Simultaneous flash and fluorescence illumination via dual illumination port adapter
  • Ultra stable output of the PhotoFluor II enables quantitative imaging of the dimmest samples
  • Optically isolated input and output flash triggers enable tight integration with your experimental protocols
  • Ability to couple to all major brands of microscopes

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